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Copper Tripeptide-1

A copper-associated tripeptide used in skin-conditioning products, often called GHK-Cu.

Sources: 1, 2
This is general ingredient information, not medical advice. Product-specific limitations and unknowns are listed below.
Skin conditioning
Also known as

GHK-Cu, Copper peptide

Pregnancy

Not assessed

No pregnancy- or breastfeeding-specific assessment has been completed for this record. A cosmetic safety review is not a pregnancy rating.

Evidence

Not assessed

Name on ingredient lists (INCI)

Copper Tripeptide-1

What it does

Used in appearance-focused skincare. Cosmetic claims require evidence for the actual peptide material and formula.

Sources: 1, 2

Good for

  • Skin-conditioning formulas
Sources: 1, 2

How to use it

Follow the finished product's directions and assess tolerance when introducing it. Ingredient research does not supply one universal dose or schedule.

Sources: 1, 2

Who should be careful

Avoid applying ordinary cosmetics to wounds or freshly treated skin unless a clinician recommends the specific product.

Sources: 1, 2

Pairs well with

No supported pairings have been documented for this record.

Usage, safety and formulation details

Mechanism of action

Copper binding and cell-signaling effects have been investigated; laboratory wound-related findings do not establish a clinical wound treatment.

Sources: 1, 2

Potential adverse effects

Irritation or contact allergy may occur; stop a product that causes a persistent or marked reaction.

Sources: 1, 2

Formulation considerations

Peptide stability, copper speciation, pH and delivery matter. Do not infer blanket incompatibility with every acid or antioxidant.

Sources: 1, 2

Pregnancy and breastfeeding

Not assessed

No pregnancy- or breastfeeding-specific assessment has been completed for this record. A cosmetic safety review is not a pregnancy rating.

Safety tags

Fragrance allergen
Not assessed

Not separately assessed in this draft.

Essential oil
Not assessed

Not separately assessed in this draft.

Drying alcohol
Not assessed

Not separately assessed in this draft.

May irritate sensitive skin
Not assessed

Not separately assessed in this draft.

What remains uncertain

  • Exact concentration, final pH and the full composition of any unprovided finished product
Clinical evidence and research

Clinical evidence

Evidence for its main benefit

Not assessed

The cited references support identity, formulation role or safety context. No standalone clinical efficacy rating has been completed for the main benefit in this draft.

Sources: 1, 2
Regulation and ingredient label names

Regulatory information

No jurisdiction-specific assessment is recorded. An inventory listing is not blanket approval.

Names on ingredient lists

copper tripeptide-1

Chemical identity and molecular structure

Chemical information

A closer look

Chemical structure

No single structure to show yet

A reviewed, unambiguous PubChem compound identifier is needed before a molecular diagram can be displayed.

DetailValueSource
material scopePubChem CID 71587328 (prezatide copper) is a reference copper complex only; it does not identify the supplied grade's composition, counterions or hydration.CIR: Tripeptide-1, metal salts and selected related peptides

Content updated 9 November 2026.

Sources (2)

Scientific sources

  1. CIR: Tripeptide-1, metal salts and selected related peptidessafety assessment · 2018
  2. PubChem: Prezatide copper, CID 71587328 (reference copper complex)chemical identity

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Products with Copper Tripeptide-1

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