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Pentylene Glycol

A diol used for humectancy, solvent functions and support of some preservative systems.

Sources: 1
This is general ingredient information, not medical advice. Product-specific limitations and unknowns are listed below.
HumectantSkin conditioning
Also known as

1,2-Pentanediol

Pregnancy

Not assessed

No pregnancy- or breastfeeding-specific assessment has been completed for this record. A cosmetic safety review is not a pregnancy rating.

Evidence

Not assessed

Name on ingredient lists (INCI)

Pentylene Glycol

What it does

Contributes to hydration-related formula feel and can help dissolve or distribute other ingredients.

Sources: 1

Good for

  • Moisturizing formula textures
Sources: 1

How to use it

Use the finished serum, cleanser or moisturizer as directed. This ingredient does not require a separate routine step.

Sources: 1

Who should be careful

An assessed cosmetic use does not rule out irritation or allergy in an individual formulation.

Sources: 1

Pairs well with

No supported pairings have been documented for this record.

Usage, safety and formulation details

Mechanism of action

Its hydroxyl groups interact with water while its carbon chain influences compatibility with other materials.

Sources: 1

Potential adverse effects

Stinging or contact reactions are possible in an individual product; many other formula components can also be responsible.

Sources: 1

Formulation considerations

Any preservation benefit must be verified in the whole product. Confirm that the material is the intended 1,2-pentanediol grade.

Sources: 1

Pregnancy and breastfeeding

Not assessed

No pregnancy- or breastfeeding-specific assessment has been completed for this record. A cosmetic safety review is not a pregnancy rating.

Safety tags

Fragrance allergen
Not assessed

Not separately assessed in this draft.

Essential oil
Not assessed

Not separately assessed in this draft.

Drying alcohol
Not assessed

Not separately assessed in this draft.

May irritate sensitive skin
Not assessed

Not separately assessed in this draft.

What remains uncertain

  • Exact concentration, final pH and the full composition of any unprovided finished product
Clinical evidence and research

Clinical evidence

Evidence for its main benefit

Not assessed

The cited references support identity, formulation role or safety context. No standalone clinical efficacy rating has been completed for the main benefit in this draft.

Sources: 1
Regulation and ingredient label names

Regulatory information

No jurisdiction-specific assessment is recorded. An inventory listing is not blanket approval.

Names on ingredient lists

pentylene glycol

Chemical identity and molecular structure

Chemical information

A closer look

Chemical structure

2D chemical structure of Pentylene Glycol, PubChem CID 93000
A 2D bond diagram. Lines represent bonds; element labels identify atoms. Carbon and many attached hydrogens are implicit.
View PubChem record · CID 93000 →
DetailValueSource
PubChem CID93000PubChem compound 93000: chemical identity
molecular formulaC5H12O2PubChem compound 93000: chemical identity
iupac namepentane-1,2-diolPubChem compound 93000: chemical identity

Content updated 9 November 2026.

Sources (2)

Scientific sources

  1. CIR: Safety assessment of 1,2-glycolssafety assessment · 2012
  2. PubChem compound 93000: chemical identitychemical identity

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