A skin-conditioning ingredient used in products for dry or uncomfortable-feeling skin.
Sources: 1, 2No alternative names recorded.
Not assessed
No pregnancy- or breastfeeding-specific assessment has been completed for this record. A cosmetic safety review is not a pregnancy rating.
Not assessed
Allantoin
What it does
Supports a smoother, more comfortable skin feel. Specific US skin-protectant drug uses have their own concentration and labeling conditions.
Sources: 1, 2Good for
- Dry-feeling skin
- Comfort-focused skincare
How to use it
Use in a finished product according to its label. Do not use a raw cosmetic ingredient as a treatment.
Sources: 1, 2Who should be careful
A soothing claim does not rule out an individual reaction. Avoid treating persistent rashes or open wounds with an ordinary cosmetic.
Sources: 1, 2Pairs well with
No supported pairings have been documented for this record.
Usage, safety and formulation details
Mechanism of action
Used for conditioning and protective effects; its presence in a cosmetic alone does not establish wound-healing efficacy.
Sources: 1, 2Potential adverse effects
An individual may experience irritation or a contact reaction despite a product's comfort-focused positioning.
Sources: 1, 2Formulation considerations
Limited solubility makes concentration, dissolution and crystallization control important.
Sources: 1, 2Pregnancy and breastfeeding
Not assessed
No pregnancy- or breastfeeding-specific assessment has been completed for this record. A cosmetic safety review is not a pregnancy rating.
Safety tags
- Fragrance allergen
- Not assessed
Not separately assessed in this draft.
- Essential oil
- Not assessed
Not separately assessed in this draft.
- Drying alcohol
- Not assessed
Not separately assessed in this draft.
- May irritate sensitive skin
- Not assessed
Not separately assessed in this draft.
What remains uncertain
- Exact concentration, final pH and the full composition of any unprovided finished product
Clinical evidence and research
Clinical evidence
Evidence for its main benefitNot assessed
The cited references support identity, formulation role or safety context. No standalone clinical efficacy rating has been completed for the main benefit in this draft.
Sources: 1, 2Regulation and ingredient label names
Regulatory information
No jurisdiction-specific assessment is recorded. An inventory listing is not blanket approval.
Names on ingredient lists
allantoin
Chemical identity and molecular structure
Chemical information
Chemical structure
| Detail | Value | Source |
|---|---|---|
| PubChem CID | 204 | PubChem compound 204: chemical identity |
| molecular formula | C4H6N4O3 | PubChem compound 204: chemical identity |
| molecular weight | 158.12 g/mol | PubChem compound 204: chemical identity |
Content updated 9 November 2026.
Sources (3)
Scientific sources
- CIR: Allantoin and related complexessafety assessment · 2010
- US eCFR: Skin protectant active ingredients, 21 CFR 347.10regulatory context
- PubChem compound 204: chemical identitychemical identity
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