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Sodium Lauryl Sulfate

An anionic surfactant used to cleanse and generate foam in suitable products.

Sources: 1, 2
This is general ingredient information, not medical advice. Product-specific limitations and unknowns are listed below.
CleansingFoam support
Also known as

SLS, Sodium dodecyl sulfate, SDS

Pregnancy

Not assessed

No pregnancy- or breastfeeding-specific assessment has been completed for this record. A cosmetic safety review is not a pregnancy rating.

Evidence

Not assessed

Name on ingredient lists (INCI)

Sodium Lauryl Sulfate

What it does

Removes oily soils and supports lather. Its cleansing role does not determine how irritating a complete rinse-off formula will be.

Sources: 1, 2

Good for

  • Rinse-off cleansing
  • Foaming systems
Sources: 1, 2

How to use it

Follow cleanser directions and rinse thoroughly when the product is designed for rinse-off use.

Sources: 1, 2

Who should be careful

Can irritate dry, eczematous or reactive skin, especially with prolonged contact. Choose a tolerated finished cleanser rather than assuming all sulfates behave identically.

Sources: 1, 2

Pairs well with

No supported pairings have been documented for this record.

Usage, safety and formulation details

Mechanism of action

The dodecyl chain and sulfate head form surface-active assemblies that help disperse oils. Exposure can also disrupt skin barrier lipids and proteins.

Sources: 1, 2

Potential adverse effects

Dryness, redness and irritant contact dermatitis may occur. Irritation is not the same diagnosis as an allergic contact reaction.

Sources: 1, 2

Formulation considerations

Concentration, co-surfactants, exposure duration and rinsing strongly affect irritation. Laboratory SLS irritation tests are not direct tests of every consumer cleanser.

Sources: 1, 2

Pregnancy and breastfeeding

Not assessed

No pregnancy- or breastfeeding-specific assessment has been completed for this record. A cosmetic safety review is not a pregnancy rating.

Safety tags

Fragrance allergen
Not assessed

Not separately assessed in this draft.

Essential oil
Not assessed

Not separately assessed in this draft.

Drying alcohol
Not assessed

Not separately assessed in this draft.

May irritate sensitive skin
Flagged

Potential concern depends on the product and exposure; this flag is not a prediction of every user's response.

Sources: 1, 2

What remains uncertain

  • Exact concentration, final pH and the full composition of any unprovided finished product
Clinical evidence and research

Clinical evidence

Evidence for its main benefit

Not assessed

The cited references support identity, formulation role or safety context. No standalone clinical efficacy rating has been completed for the main benefit in this draft.

Sources: 1, 2
Regulation and ingredient label names

Regulatory information

No jurisdiction-specific assessment is recorded. An inventory listing is not blanket approval.

Names on ingredient lists

sodium lauryl sulfate

Chemical identity and molecular structure

Chemical information

A closer look

Chemical structure

2D chemical structure of Sodium Lauryl Sulfate, PubChem CID 3423265
A 2D bond diagram. Lines represent bonds; element labels identify atoms. Carbon and many attached hydrogens are implicit.
View PubChem record · CID 3423265 →
DetailValueSource
PubChem CID3423265PubChem compound 3423265: chemical identity
molecular formulaC12H25NaO4SPubChem compound 3423265: chemical identity
molecular weight288.38 g/molPubChem compound 3423265: chemical identity
iupac namesodium dodecyl sulfatePubChem compound 3423265: chemical identity

Content updated 9 November 2026.

Sources (3)

Scientific sources

  1. CIR: Final report on the safety assessment of sodium lauryl sulfate and ammonium lauryl sulfatesafety assessment · 1983
  2. PubChem: Sodium lauryl sulfate identity and irritation contextchemical identity and safety
  3. PubChem compound 3423265: chemical identitychemical identity

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